If You’re Going to Solo Trip on Psychedelics Bear This in Mind

If you’re new to the use of psychedelics, it’s best to try a small dose and observe your reactions. Also, avoid loud, discordant music or beats. Observing your reactions to the substance is essential for determining how much to take and how long to spend in a state of high. If the experience is too long, consider a lower dose or a shorter trip.

Global Drug Survey Suggests

Experts warn against going on a solo psychedelic trip. One such expert is Ben Sessa, a psychiatrist in the UK who has studied the therapeutic effects of psychedelics for 15 years. While he does not reject the possibility of a solo psychedelic trip, he does suggest that you keep this information in mind.

One of the fascinating aspects of psychedelic drugs is how they work in the brain. By increasing entropy, they allow communication between different neural regions. They also suppress the activity of the default-mode network, which is involved in self-conscious thought. Researchers suggest that psychedelics help people dissolve their ego and experience mystical, transcendental experiences.

Another benefit of solo trips is reconnecting with yourself and focusing on your own needs. Self-care is critical when you’re on psychedelics. You’ll be able to focus on what you need to do to live a happier, more fulfilling life. You’ll also get to spend some quality time with your sober partner, who can reassure you.

The first wave of psychedelic research failed due to over-exuberance about the potential of psychedelic drugs. People who embraced psychedelics thought they had the power to change the world, and they had trouble justifying confining them to a laboratory. They felt they should be used for the benefit of the sick. Even once respectable scientists grew frustrated with a scientific method that relied on objective measurements. Psychedelics were viewed as disruptive in the 1960s.

Using Psychedelics to Self Treat

Using psychedelics to self-treat when going on a solo trip sounds like an old-fashioned hobby relegated to your grandmother’s decorative pillows. But it’s not so bad if you’re willing to follow some basic guidelines. Psychedelics are powerful tools for healing, but they can also create unpleasant experiences. You need to make sure that you’ve given yourself time to recover before embarking on a trip.

If you’re interested in trying psychedelics for mental health, you should know there’s a high risk of developing a mental illness. While the potential benefits may be more significant than you think, it’s vital to seek the support of a professional if you have a history of mental illness or are at high risk of developing a mental disorder. It’s also important to note that the therapeutic use of psychedelics is much safer than trying them during a music show.

One of the best ways to cope with dramatic experiences is telling stories. Retelling these stories is an effective way to structure and understand the dramatic experience. Narrative work connected psychedelic users to a larger community and helped them make sense of a problematic experience. Ultimately, using psychedelics for self-treating can be an excellent way to explore the benefits of these drugs and make the most of your trip.

Potential Efficacy to Treat

Although taking drugs is generally considered a social activity, many people use illegal substances on their own. Heroin and ketamine are popular choices to self-medicate emotional pain and dissociate from boredom. According to the Global Drug Survey, increasing numbers of people are self-medicating with psychedelics to overcome depression, addiction, or end-of-life anxiety.

Early research indicated that LSD, Molly, or ecstasy, can help those recovering from substance use. However, recent research supports the notion that psychedelic therapy shows promise as a treatment for addiction. In an interview with Verywell Mind editor-in-chief Amy Morin, a psychotherapist, about the psychedelics’ potential to treat addiction, she talks with renowned psychedelic researcher Brian Pilecki about the therapeutic benefits of psilocybin for PTSD and other mental conditions.

In a study of 300 alcohol-addiction sufferers, psychedelics reduced the use of alcohol in a study of three types of alcoholics. A large majority of participants in the study reported that their alcohol consumption had decreased after taking psychedelics, including LSD and DMT. Several reports from alcohol-abuse recovery centers further confirm this research.

Although the results of this study are preliminary, further studies are needed to determine whether or not these drugs help treat depression. As of 2017, the FDA and the Israeli Ministry of Health have approved MDMA for use in patients who have PTSD. MAPS is now working with VA hospitals to train more facilitators in the field, and Doblin plans to administer the drug to veterans who have PTSD.

Pick Your Set and Setting Wisely

The best psychedelic trips begin with the proper set and setting. Make sure you’re in a space where you can relax, connect with nature, and resolve your goals. Psychedelics are potent medicines that can help you get through emotional pain and trauma. To get the most out of your trip, pick a location that enables you to be alone.

The first trip should be the easiest to handle. Try to avoid high doses and high settings. You’ll be more comfortable with your dose if you’ve successfully managed the previous trip. Remember that a bad trip can be caused by many factors, including the wrong Set & Setting. Don’t overdose yourself. Start with a small dose if you’re not sure whether you can handle the high.

If you’re a first-time psychedelic user, it’s essential to seek out support from someone who has taken similar substances before. A former user or guide can offer support if you’re experiencing a difficult experience. A trusted friend or relative who doesn’t judge you can also be a great confidante. The Fireside Project even offers a peer support hotline and an app. If you do encounter a problem, contact emergency services.

Turn on, Tune in, and Don’t Freak Out

When you’re planning a psychedelic solo trip, it’s helpful to watch a documentary about the positive effects of psychedelics. If you’re going on a solo trip on psychedelics, you should have a buddy who can coach you back down from the high. It’s also helpful to bring an image-laden card to show yourself to a friend. Remember that psychedelics are highly unpredictable, and you should try to keep an open mind and not expect too much.

Integrate Your Psychedelic Experience into Your Life

The integration stage of your psychedelic experience is perhaps the most critical part of the experience. The growth and learning you’ll experience during the trip are not only psychological but also spiritual. While tripping outside of a clinical setting, it’s easy to fixate on your expectations before the trip begins, so it’s essential to keep an open mind. You can also prepare for the trip by making a set of intentions or by using an image-laden card to guide your journey.

Usually, psychedelics are paired with practices that confirm or extend the altered states. This spiritual connection is often missing in secular contexts, and without it, the experience may not be meaningful. Fortunately, shamanic traditions are available to help you process your psychedelic experience and make it more meaningful in your life.

The goal of PHRI is to help patients integrate a psychedelic experience into their lives. While this method does not involve the administration of psychedelics, therapists must understand the unique needs of patients and determine what they consider successful integration. Although integration sessions can be helpful, sometimes challenging experiences can occur even with adequate planning. These challenges can be overwhelming for both the patient and therapist. If the experience is challenging, the therapist can help them cope with the challenges that come along the way.

A trained therapist can guide the difficulties of integrating a psychedelic experience into your life. A therapist may also offer advice on which mushrooms to take. Some therapists specialize in psilocybin therapy, while others are familiar with the effects of psychedelics. Regardless of your intentions, always consult with a trained therapist before making life-changing decisions.


Wearable Psychedelics Could Soon Give Users Maximum Control Over Their Trip

Wearable psychedelics could be coming soon, giving users the ultimate level of control over their experience. The adjustable subcutaneous device from Bexson gives users the ability to tailor their trip, setting the intensity, depth, and duration of the experience. The device also allows users to change the settings and dosage on the device during a trip. The wearable psychedelics would be monitored by a healthcare provider and regulated by a medically-approved dosage.

There are a variety of companies developing wearable psychedelics. The company’s products will allow users to use psychedelics without a doctor. The company also expects to launch a clinical trial for its psychedelic-assisted therapy. The pharmaceutics isn’t available yet, but the team plans to continue working on the products and developing a pharmaceutical.

Bexson Biomedical Develops a Wearable Ketamine Pump

Bexson is working with medical packaging manufacturer Stevanato Group to manufacture its wearable ketamine pump. Its founders, Gregg Peterson and Jeffrey Becker believe that ketamine can offer an alternative to opioids and have partnered with a psychiatrist.

Bexson Biomedical is developing a wearable ketamine pump that works on the principles of an insulin pump. It is designed to be implanted into the body, delivering a dose of ketamine to the brain in the appropriate amounts to create the desired effect. The company claims that the wearable ketamine pump works by releasing 20 to 70 milligrams of ketamine in a slow drip. The dose is low enough to cause no hallucinations but high enough to create a psychoactive effect. The dosage of psychedelics is not standardized, so the ideal dosage varies from person to person. In addition, the length of the trip varies with the user’s metabolism and liver enzymes.

The device could be in human trials as early as 2022. The perfect psychedelic dose differs from person to person and lies somewhere between the “is it working?” And the “run! The moon is chasing us!” Stage. However, scientists are trying to develop better delivery systems.

Wearable Psychedelics Could Give Users The Maximum Control Over Their Trip

The new technology can revolutionize the way that psychedelics are administered. The subcutaneous Bexson pump allows users to fine-tune their psychedelic experience. They can pre-program how deep they want to go, how long they want to stay in the trance state, and how much to take. Once the device is appropriately tuned, users can increase their infusion rate to reach the desired level of experience. However, this requires careful monitoring by healthcare professionals to avoid overdose.

Wearable psychedelics could give users greater control over their trips. Researchers are working to develop a device that can deliver precise doses of psychedelics through the skin. This new technology could allow people to fine-tune the length and intensity of their psychedelic experience, and it might even allow them to pre-program their psychedelics. The adjustable subcutaneous device would be similar to an insulin pump and allow patients to program the duration and depth of their psy-trips themselves.

Wearable psychedelics could soon give users maximum control over their trip. The device works by allowing users to take the drug without leaving their homes. The pump is compatible with most electronic devices and is designed to deliver the drug to the body subcutaneously.

Bexson Biomedical Plans to Conduct Human Trials in 2020

Bexson Biomedical has partnered with medical device maker Stevanato Group to develop a wearable ketamine device. The company has already produced a ketamine microdosing device for clinical trials. It is only available in the Netherlands, but the company hopes to introduce it to the general public by 2022. The company has stated that it plans to conduct human trials in 2020 and aims for FDA approval in 2025 or 2026.

The company has partnered with the Lieber Institute for Brain Development and is advancing multiple unnamed drug candidates through the discovery stage. As long as these trials go well, the product could be available in the market as early as 2022. These companies have a long track record in developing psychedelic products and are now announcing a successful launch.

MINDCURE Working on Developing Ketamine-assisted Psychotherapy

In the meantime, several other companies are aiming to develop wearable devices. MINDCURE is a biotechnology company that is working on developing ketamine-assisted psychotherapy. It plans to develop these products in the future and expand its offerings into other psychedelic substances. The first product is a prototype that allows users to experience ketamine.

Improve The Way Ketamine is Administered to Provide Psychedelic-assisted Psychotherapy

One private company has launched a project that is working to provide psychedelics-assisted psychotherapy. The company aims to leverage genomic and biological information to improve the way ketamine is administered. It also plans to open its clinic in Jamaica, focusing on psilocybin-assisted therapy for eating disorders.

There is a Growing Psychedelic Industry

While these technologies are still in the early stages, there is a growing psychedelic industry. This sector is growing fast, and some companies are already making psychedelic products that are more accessible and affordable than current methods. Bexson Biomedical, for example, is working with three DEA-approved laboratories to develop a psilocybin-based drug.

The technology is mainly for medical use and should be safe for recreational use. It is not yet commercially available. Its use in the medical community is not limited to recreational purposes. It could even be used for therapeutic purposes in the future. It is also used to treat substance-related disorders, such as addiction. It will also be available in a wearable form for the general public.


New Zealand Researchers Study The Effects of MDMA For Tinnitus Treatment

Research has shown that MDMA may treat tinnitus. The drug has been used to treat other conditions such as migraines, epilepsy, and glaucoma. Although the treatment does not provide a permanent cure for tinnitus, it has been shown to alleviate its symptoms. It is important to note that the drug is illegal to obtain and is not recommended for anyone suffering from the condition.

New Zealand Researchers Study MDMA for Tinnitus

MDMA, the active compound in party drugs like ecstasy, was shown to effectively treat tinnitus. Previously, MDMA was used as a treatment for mental health disorders. It has been shown to reduce the ringing sensation in the ears, and the drug is a world-first for tinnitus treatment.

The study used MDMA, a recreational drug popular in the club scene, to treat patients suffering from tinnitus. The researchers reduced the severity of the patients’ tinnitus symptoms by 80 percent. While tinnitus is not a disease, the condition can be debilitating. Since it is not a common cause of hearing loss, it’s challenging to determine which cause of tinnitus is responsible. However, successful treatment can help relieve the ear noise and improve the patient’s quality of life. Regardless of the underlying cause, MDMA may be an effective tinnitus treatment.

The researchers used brain imaging to differentiate between placebos and MDMA. MRI images can help determine whether patients received the actual treatment or a placebo. This research could lead to a new class of drugs for tinnitus. In the meantime, tinnitus is an annoying and painful condition, but a placebo does not affect this.

Researchers at the University of Auckland are testing the effects of MDMA in treating tinnitus, the condition that causes a persistent, ringing sound that no one else can hear. These trials have taken place in the past two years and involved a small number of people. Participants were given a small dose of the drug or a placebo. The researchers did not want participants to feel ‘high,’ so they administered a small dose of MDMA without the ‘high’ effect. Researchers administered a single dose of 30 or 70 mg of the drug in the study. The researchers monitored them for four hours. After three hours, the participants with the MDMA-induced tinnitus reported a corresponding reduction in the amount of noise they could hear. Meanwhile, the placebo group reported a significant placebo effect. The researchers dispensed MDMA in varying doses, with a high dose causing euphoric effects.

Those who did experience the benefits reported them for a week or more. The study also employed pharmacists to dispense the medication to avoid possible issues.

MDMA Could Help Patients With Tinnitus

The study found that MDMA could help patients with tinnitus. However, the research is limited because only 0.5% of the population suffers from severe cases. There is a vast market for this drug, so it’s essential to consider the cost and the safety. It may be too early to tell if it will work, but it is a promising step in the right direction.

Another recent study aims to treat tinnitus using MDMA. Known as the “rave drug,” MDMA is the active ingredient in ecstasy. The drug is widely available and can relieve tinnitus in small groups. The drug may also be used to treat many other types of tinnitus. The study results are preliminary and should be repeated if the drug is effective.

In some studies, MDMA may have beneficial effects for tinnitus treatment. In a double-blind, randomized cross-over design, the study found that a small drug dose significantly reduced tinnitus sufferers’ symptoms. The drug has a positive effect on tinnitus and may be an effective alternative to conventional treatments for tinnitus.

More Research Needs to be Done

Several recent studies have suggested that MDMA may be effective in reducing tinnitus. The drug is similar to an antidepressant that works to relax the brain. The new research demonstrates that taking MDMA can significantly reduce tinnitus severity.

The study’s results show that MDMA users had a marked reduction in tinnitus symptoms than placebo users. However, it did not say how many people reported the complete disappearance or how many experienced an adverse reaction to MDMA. Ultimately, the researchers concluded that it would be too early to conclude this study. Moreover, it’s not clear if this drug is an effective treatment for tinnitus. They are confident that MDMA will be legalized soon, like psychedelic mushrooms. In the meantime, the drug is a promising step forward.


MDMA Medicine For PTSD Has Shown Promising Results

MDMA medicine for people with PTSD has been gaining popularity in recent years. Its effects include helping people develop greater trust and bringing repressed traumatic memories to the surface. These drugs can also help people reduce the fear associated with traumatic memories. However, the FDA has not yet approved the use of MDMA as medicine for people with PTSD. A Phase III trial is currently underway, but the preliminary results are promising. It is possible that the FDA could approve the drug as early as 2022.

Researchers conducted a randomized trial in which they compared the effects of MDMA on people with PTSD with a placebo group. The drug is thought to work by soothing the amygdala, the part of the brain that acts as a smoke alarm and warns the body to prepare for danger. In individuals with PTSD, the amygdala can become overactive and react to even the slightest events.

MDMA Medicine Can Reduce the Symptoms of PTSD

There are several reasons why MDMA medicine can reduce the symptoms of PTSD. The drug reverses how your brain works when a traumatic experience triggers you. It does this by increasing activity in the prefrontal cortex, which regulates your emotions. This allows you to overcome feelings of fear and anger. It also improves your empathy and introspection. In addition, MDMA increases the production of two hormones in your brain associated with bonding and intimacy.

This substance is also a powerful mood enhancer. It helps you feel more relaxed and focused. Studies have shown that it reduces PTSD symptoms in up to 80% of people who took it. This means that if you have PTSD, this medicine may help you reduce your symptoms. It is important to note that this treatment has not been approved for medical use in the United States. You must have a prescription to take it.

Psychotherapy and Antidepressants Have Not Been Effective For people with PTSD

Fortunately, there are other treatments available. Psychotherapy and an antidepressant are the current gold standard treatments for PTSD. These include selective serotonin reuptake inhibitors, anxiolytics, and sedatives. These methods have proven to be ineffective in treating PTSD. However, these therapies do have some benefits. In some cases, the drug can even help you overcome the symptoms of PTSD.

MDMA Could Significantly Lower Symptoms of PSTD

The effectiveness of MDMA medicine in reducing PTSD symptoms was also confirmed in a recent study. The drug reacts with the body so that it can induce empathy emotion. This emotion is critical in establishing more effective relationships with therapists and effectively sorting through trauma. Many studies have shown that these treatments improve PTSD symptoms in three to six sessions. The researchers concluded that this treatment could significantly lower the symptoms of PTSD.

MDMA medicine has shown promise in treating PTSD. Its effect on the brain causes it to change its alertness state. It releases helpful chemicals and allows the brain to let loose and work out its issues. This is beneficial for people who have PTSD. In addition, it also reduces symptoms of depression. Moreover, MDMA is a popular alternative medicine used to treat various medical conditions.

MDMA is an effective treatment for PTSD. It can help patients with symptoms of PTSD. It can also be used as an assistive aid for other medical conditions. It has been shown to reduce the symptoms of PTSD. The drug alters the brain’s alertness state and releases positive chemicals, which help patients work through their problems. Therefore, MDMA can reduce the symptoms of PTSD. There is no reason for this to be a promising treatment for PTSD.

MDMA Psychotherapy is a Promising Alternative

MDMA-assisted psychotherapy is an experimental treatment for trauma and psychological suffering. However, this method has many challenges. It is not a “magic pill” and cannot heal all forms of trauma or psychological suffering. It may only facilitate a part of the process and may not answer all of your problems. Instead, it should be used in the context of psychotherapy. It is essential to understand that this therapy is not a cure-all but a stepping stone.

Research needs to be conducted on a large-scale sample size to determine whether MDMA-assisted psychotherapy is safe. The study will examine how patients respond to treatment and their outcomes. The primary outcome measure will be the change in the CAPS-5 score from Baseline to Primary Endpoint. The secondary outcome measure will be the number of suicidal thoughts reported after the treatment, measured by the Columbia Suicide Severity Rating Scale. During the experimental session, MDMA is administered with therapy.

Clinical trials have shown that MDMA-assisted psychotherapy can be effective for post-traumatic stress disorder (PTSD) patients. Researchers have received a breakthrough therapy designation in the United States and are now conducting Phase 3 trials to find if MDMA can help treat other disorders. Alcohol use disorder and PTSD share several similarities, making it possible for the drug to be used as an adjunct to psychotherapy. The drop-out rate is similar in both conditions, and recurrence of symptoms is common.

Although MDMA medicine for people with PTSD is still controversial, some studies show that it can help reduce PTSD symptoms. The drug stimulates the release of oxytocin, a hormone that makes us feel safe at the moment. Moreover, the effects of MDMA treatment continue for months after the treatment is over. Therefore, MDMA-assisted psychotherapy is a promising alternative to conventional therapy.


The First Trial to Study the Effects of Microdosing LSD

Microdosing LSD (or magic mushrooms or other psychedelic drugs) is the act of consuming very low doses that don’t have any significant effects on the entire body. Yet, they have a significantly limited impact. Defenders of this strategy say that microdosing LSD has pharmaceutical advantages with next to no drawbacks. In contrast, researchers are still questioning the effects of microdosing LSD since much more research needs to be done. 

The Research on Microdosing Psychedelics

Microdosing hallucinogenics have been growing in consideration lately, as it’s been said to enhance imagination, concentration and reduce the heaviness of sorrow. Now, researchers need to determine whether utilizing low quantities of these substances benefits the experiences users get. 

On Sept. 3, analysts from the Beckley Foundation and Imperial College of London became the first to study to explore the advantages of microdosing LSD. If the study works out positively, it could give us vital bits of knowledge into the domain of different hallucinogenic use.

Microdosers will generally use a little dose of LSD – just one-fifteenth of a tab – or psilocybin. The review selects only the individuals who use LSD since there is some trouble masking even ground-up mushrooms in a container.

However, it’s illicit. So the number of individuals that are microdosing is obscure, and there is not that much evidence of the impacts and drawbacks. In a request to find out more, the Beckley Foundation, which was set up to lead the examination into mind-altering substances, will be the first to study the effects of microdosing LSD on Monday, Sept. 3, 2018. 

Researchers need to know whether or not microdosing hallucinogenics produces evident, positive outcomes in people. When an individual microdoses hallucinogenics, they will, for the most part, take a small dose of LSD or magic mushrooms. The idea is that these minute dosages are too small to create an out-of-body hallucinogenic experience, however enormous enough to actuate and stimulate the cerebrum. Numerous users have found that microdosing LSD has profound changes in their everyday lives. Hence, the researchers are hoping to determine whether individuals who report positive outcomes from microdosing are experiencing benefits from the drugs.

Since it would be restrictively costly to complete a customary study with illegal drugs (also, it would be nearly difficult to get endorsement for it), Balázs Szigeti, the review chief, conducted a “self-blind” study — welcoming individuals to take a microdose. These individuals will complete surveys and tests. 

Individuals who currently microdose, however, may be biased. They are accomplishing something novel and energizing, and they have confidence in – and realize they are doing it. It is nothing unexpected that they are getting a constructive outcome. 

How the Study Works

The people who volunteer to participate will be sent a manual that illustrates how to take the little piece of smudging paper stacked with a portion of LSD. After making the dosages, the volunteers will have a unique QR code to follow on which days they took LSD or a placebo. Then, all of them will be fixed and rearranged up at that point. By then, the volunteers won’t know which envelopes contain hallucinogenic or placebos. This adequately randomizes the study and keeps the subjects unaware about taking a microdose. 

The Swiss researcher Albert Hofmann, who initially took LSD in 1936 and started taking it years after the fact, was said to have microdose in his advanced age. The people who do it discuss a feeling of euphoria and are able to concentrate with none of the super stimulating sensations related to the drug. “It has become famous in Silicon Valley as a method for expanding inventiveness and usefulness,” said Szigeti. “I was keen on this and checked out the analytical writing. To my extraordinary astonishment, I found there were zero examinations on microdosing. Assuming you go online, a significant number of individuals are expressing exceptional results.

Amanda Feilding, an overseer of the Beckley Foundation, has microdosed on LSD and supports the benefits hallucinogenic drugs provide. “Since I originally found out with regards to LSD in 1966, preceding it was made unlawful, I became mindful of the incredible benefits it gave to my well-being and intellectual improvement,” she said. She also said that she gets a great deal of correspondence on microdosing from San Francisco. “I think it is spreading, yet it is difficult to tell since most people still don’t know about the potential benefits LSD can give us all. There has been a ton of talk about it over the most recent couple of years.” She says she considers it “nearly as a psycho-nutrient” at low dosages.” People have announced that it has lifted their depression, while others say it causes them to have a more energized outlook on their work. “One can’t and doesn’t have any desire to urge individuals to microdose, yet it is fascinating to attempt to assemble information in a somewhat more logical manner from individuals who are doing it,” she said.

David Erritzoe, who is chipping away at the study with Szigeti, said it is “in all ways an uncommon task” steered with a bit of gathering these individuals. Microdosing on LSD has been proven to be beneficial to our well-being. He and Szigeti say assuming the outcomes are fascinating, more traditional studies on microdosing LSD need to be done.


How Magic Mushrooms Have Been Helping Life Long Addicts Stop Smoking For Good

Despite the many gums, patches, and other cessation products available, it remains challenging for longtime smokers to kick their cigarettes to the curb. This is particularly true of smokers unfortunate enough to take up the habit as teenagers; in addition to fighting the effects of nicotine, these individuals must escape the neural pathways established over several years or even decades. Even if cessation is accomplished for a brief period, the chances of relapse are incredibly high among lifelong cigarette addicts.

Researchers are beginning to acknowledge that the traditional cold turkey approach to smoking cessation is ineffective for the vast majority of smokers. New solutions, although often controversial, are gaining traction. Such is the case for magic mushrooms, the shocking new approach to smoking cessation that, according to a recent study, accomplishes the impossible: it allows smoking addicts to quit with minimal effort!

Magic Mushrooms and Smoking: The Study

Drug users have long claimed that substances such as marijuana and, yes, magic mushrooms can switch up lifelong smoking patterns. Until recently, however, these arguments were regarded as the ramblings of stoners. 

A report published in the Journal Of Psychopharmacology has changed all that, indicating that, perhaps, mushrooms can end hardcore cigarette addictions.

The landmark study took place not in a dingy backroom, as skeptics may suspect, but at the highly reputable cognitive behavioral therapy program at the Johns Hopkins University School of Medicine. Fifteen participants, all lifelong smokers, were asked to supplement their cigarette cessation efforts with magic mushrooms. All had tried to quit cigarettes in the past and failed; the vast majority had never used mind-altering drugs before the study. Participants were asked to leave cigarettes cold turkey instead of taking three separate doses of the drug over several weeks.

To the surprise of researchers, the ensuing abstinence rate was far higher than initially predicted. Eighty percent of participants were still cigarette-free six months after the study ended. Compare this to a success rate of less than thirty percent for traditional nicotine therapies, and it’s easy to see why this study has the smoking cessation community so excited.

Study Implications and The Need For Future Research

Although proponents of mind-altering drug treatments point to the Johns Hopkins study as irrefutable proof of the efficacy of magic mushrooms, more research is needed before this potential treatment can go mainstream. 

The study only featured fifteen participants, so it is difficult to say whether the results would be as promising if a larger group of smoking addicts tried mushrooms. Even if further research proved the efficacy of mushrooms, it would be impossible to administer this treatment in standard hospitals and clinics without significant changes to current drug laws. 

However, in some countries where mushrooms are legal, this approach to smoking cessation may eventually achieve mainstream status.

Experts advise those interested in mushroom treatment to avoid partaking in yourself approaches; devastating legal consequences are likely, and what’s more, magic mushroom use has only proven effective when doses are taken very occasionally, under the supervision of medical professionals.


Shrooms or Magic Mushrooms: How Much is Safe, The Benefits, and Risks

Shrooms or Magic Mushrooms are a part of a mushroom family that contains psilocybin. Psilocybin is a compound found in more than 200 species of mushrooms. It is a natural psychedelic prodrug compound. These species are collectively called psilocybin mushrooms.

Psilocybin found in hallucinogenic mushrooms or shrooms is classified as a “Schedule I” drug. It currently has no accepted official use in medical treatment in the United States, United Kingdom, or other regions. The fear with magic mushrooms is that they have a high probability of misuse because of their mind-altering capabilities, and they might be addictive for some people.

Is It Safe to Eat Shrooms?

You can eat shrooms in a moderate amount, but not everyone has had a good experience with them. They can be mixed with food.

You can brew magic mushrooms like tea for drinking. These are not for everyone; if they do not suit you, you might experience unpleasant bad trips.

One can also mix them with tobacco or cannabis and smoke.

According to U.S. government statistics, shrooms have been used by over 22.8 million American citizens at least once.

Shrooms are constantly being a subject for many medical types of research such as to overcome stress, depression, addictions, anxiety disorder, eating disorders, and overall well-being of an individual.

Psilocybin might be a great help in reducing the pain resulting from social rejection.

How do Shrooms Work in Your Body

Researches have shown that psilocybin increases communication between areas of the brain that generally don’t communicate with each other.

Psilocybin is considered “classic psychedelics” because it can bring changes in perception, thought pattern, and mood swings by mimicking neurotransmitters in your brain similar to other addicting drugs, such as mescaline and lysergic acid diethylamide (LSD).

Once psilocybin found in shrooms enters one’s body, it is broken down into psilocin, a compound known to activate a specific type of serotonin receptor in the brain that triggers its psychedelic effects.

What Can Magic Mushrooms do to a Person

Shroom’s hallucinatory effects can make a person:

  • See geometric shapes 
  • Hear sounds
  • Feel sensations that seem real to the person but are imaginary
  • They may feel like they can smell colors
  • You may feel euphoric and light as it induces mood swings
  • You may feel very relaxed
  • You may feel giggly
  • You might feel more open

Magic Mushrooms May Have Powerful Long-Term Benefits

Scientific American Griffiths coauthored an article with his fellow Heffter board member, Grob. 

According to the article:

  • Most of the participants experienced a greater sense of inner fulfillment
  • Increased self-confidence
  • Improved social confidence
  • An increase in overall well-being
  • An increased ability to tolerate problems and frustration
  • Decreased nervousness
  • Ratings of their behavior by friends, family members, and work colleagues uninformed about the drug experience were consistent with the participants’ self-ratings.

Recognizing Shrooms:

  • There are over 200 species of Mushrooms having psilocybin. 
  • Shrooms have long, grayish stems.
  • They have dark brown caps with light brown or white color in the center.
  • Dried mushrooms are rusty brown with isolated areas of off-white.

Potential Risks of Taking Shrooms, “Bad Trips”

A survey consisted of almost 2,000 people who said they had a past negative experience taking shrooms. More than 10 percent said they believed their worst “bad trip” had put themselves or others in bad situations.

Based on the research data that assessed each subject’s absolute worst bad trip:

  • 10.7% of the subjects reported that they put themselves or others at risk for physical harm during their bad trip
  • 2.6% reported they acted angrily, aggressively, or violently
  • 2.7% reported they sought medical help

If you are suffering from anxiety or bipolar disorder, magic mushrooms might worsen their symptoms.

You might experience a bad trip, which includes:

  • Negative physical symptoms such as chills, vomiting, nausea, or headaches
  • Unpleasant psychological phenomena such as paranoia or anxiety

Fresh Mushrooms Are Highly Popular in The USA

According to the report, the U.S. per capita consumption of fresh mushrooms (not magic mushrooms) amounted to approximately 3.95 pounds in 2018. White mushrooms made up 61.2 percent of U.S. mushroom sales in 2015.

Do They Have Any Withdrawal Symptoms

Shrooms usually do not have any physical symptoms of withdrawal after you stop using them. Some people might experience psychological effects, which may include anxiety and depression. You should consult a physician if you face any withdrawal symptoms.

Are Magic Mushrooms Addictive?

This question is still debatable that whether magic mushrooms or shrooms are addictive or not. Someone can become addicted to any substance or habit if they overdo or overuse it.

Some people may prefer to combine psilocybin mushrooms with another substance such as LSD to increase the effect. If this is the case, individuals have more chances to become psychologically addicted to magic mushrooms than physically addicted.

The severity of addiction to these things often depends on the number of mushrooms someone is taking. People may become addicted to it because of its mind-altering capabilities and power to make you feel relaxed, just like people can become addicted to alcohol or weed.


How Much Is A Microdose and Setting an Intention When Microdosing Magic Mushrooms

People all around the world are turning to a milder side of psychedelics to seek improvements in their lives. Microdosing psilocybin, a compound found in magic mushrooms, has become an exciting way to experience life better. Some people are using it to boost their creativity, some enhance their senses, and some are treating mental health issues such as depression, anxiety, and PTSD.

What remains unclear in all this is; how much is a microdose exactly? Does it differ from one person to another, or is it one size fits all? In this article, this is precisely what we will delve into.

What Is an Average Microdose?

In a scientific study on several human subjects, different doses of psilocybin were tested to discover that a range of 0.5 to 2.0 mg is reasonable for most potential microdoses, depending on their tolerance to the substance.

Deciding Factors

Specifying the exact quantity of psilocybin required for an ideal microdose is not enough. How is 0.5 to 2.0 mg going to translate into the dried shrooms you have lying around in your fridge? How do you even know the amount of psilocybin contained in a particular batch of mushrooms?

Well, the answer depends on a variety of factors. First, what part of the mushroom are you going to be consuming. The cap and stem each contain a specific amount of psychedelic substance. Secondly, the soil and environmental conditions matter a lot. In fact, between two different batches of the same species of shrooms, the amount of psilocybin can significantly vary. However, some rough calculations can be made despite all these factors.

Some Mushroom Math

It is still not clear whether the entirety of psilocybin converts to psilocin in the human body. The research is ongoing, but we know that different bodies can metabolize substances in myriad other ways depending on their health, sex, body type, and the compound salt form. When calculating doses, these aspects are not kept in mind. So, we may not be able to tell how much psilocybin is being delivered to the brain!

Calculating Psilocybin

While difficult, it is still possible to calculate the approximate amount of psilocybin in any given batch of magic mushrooms, provided that you are aware of the species’ name.

In his book titled Psilocybin Mushrooms of the World, Paul Stamets estimated the amount of the substance in 12 different species of dried shrooms. He also mentioned that his numbers are inflated, and most people will collect mushrooms on the lower end.

To calculate yours, you can use the following formula:

  • Weight of dried mushrooms in grams x percentage of psilocybin in the particular species / 100

However, most people who microdose also factor in the amount of psilocybin contained in the mushroom, as it is considered an active compound and can increase the intensity of the dose.

Once you have calculated the right dose, test the mushrooms with an Ehrlich Reagent testing kit to make sure they are pure. 

Setting an Intention

Before you begin a task, you already have the result in mind. You know where you have to go and how you will get there—setting an intention when microdosing psilocybin is kind of like that—except that you don’t have the result in mind, just what you want to achieve.

You may have heard that psychedelics are the only drugs that do what you want them to do. If you are still confused about it, you have come to the right page. Let’s delve deeper into what an intention is and how it can help you better your microdosing experience.

Intention vs. Goal

First, let’s differentiate between an intention and a goal. They may be similar in theory, but a choice is more than just passively thinking about a plan. It adds meaning and breathes life into your goals, while a goal would be something specific, persistent, and mainstream.

For instance, your goal when microdosing psilocybin could be that you want to change your allopathic medication for a more natural alternative.

However, your intention when taking the drug would be completely different:

  • To nurture connections with your loved ones
  • To bring about positive change in your life
  • To let go of negative emotions that cause you pain
  • To get over your past traumas
  • To embrace change
  • To seek spiritual growth—or anything that you think is holding you back in life.

In other words, an intention is heart-driven and not an entirely reasonable goal.

Discovering Your Intention

Not everybody is aware of what they want in life. If you’re going to discover what would heal you spiritually or make your life more meaningful, you should make this your intention: I intend to figure out how to make my life more spiritual and meaningful.

You can also think about what matters most to you in life, what aspects of life you want growth in, and when you feel the happiest. You could also think about the things you are grateful for or the thoughts that keep you from growing. Answering all these questions could help pave your way into a happier and more fulfilling future than you could have had before.

Become Effective and Empowered

Setting an intention helps give your thoughts a specific direction once the psychedelic experience has begun. Be clear about your goals in life, and you will be able to achieve them better through the magic that is psilocybin.

Moreover, you could also take this opportunity to become more empowered and proud of yourself. You may often find yourself thinking that you aren’t good enough or worthy enough to achieve what you want in life. If this is the case, microdosing psilocybin can help you experience not only the world but yourself in a different light.

Right before you take your microdose, set a few minutes aside to think about what you want to accomplish that day. If you are passionate enough about your intention, your day is bound to be eye-opening and spiritually revealing.


Psilocybin, IQ, and The Stoned Ape Hypothesis

Does consuming psilocybin increase IQ scores? There are many reasons this is of particular interest. For one, we have been looking for an “IQ pill” for a long time now with no luck. The main choices are nootropics like modafinil, Adderall, etc. Unfortunately, these don’t seem to work too well. Second, there are obvious benefits to a higher IQ, particularly in the labor market (Gwern, 2016; Strenze, 2015; Salgado and Moscoso, 2019). Third, as I will discuss shortly, even a minimal but significant increase in intelligence due to psilocybin may have some exciting implications for the so-called Stoned Ape hypothesis.

Why might psilocybin increase IQ scores? Well, the main driver of these effects would be neurogenesis. Many studies have found that psychedelics play a significant role in improving cognitive functioning through depression, fixing minor debilitative disorders, and abolishing the conditioned fear response in the brain.

Study in Rats

Catlow et al. (2013) injected one group of mice with a low dose of psilocybin and another with saline. They found the psilocybin injected group gained new neurons in the hippocampus. Before the mice were given psilocybin, they were placed in a freeze monitor box where they were conditioned into a fear response. This conditioned fear response was significantly reduced in the psilocybin treated group. In rats, other tryptamines were associated with increased dendritic arbor complexity and dendritic spine growth and synapse formation (Ly et al., 2018).

Clinical Study

We can rationally expect these effects to translate to humans due to the success of treating depression with psilocybin. A clinical study gave 12 patients with treatment-resistant depression psilocybin. The participants received two total doses, each very low to moderate size and seven days apart. They found that there were significant reductions in depression (Carhart-Harris et al., 2016). Unfortunately, there was no control or placebo group, so proving the causality is difficult.

But, when the treatment group has a treatment-resistant major depressive disorder and faces substantial effects over a long time, it is unlikely this was due to a placebo effect or a random happening. Carhart-Harris et al. (2017) found similar results in strong effectiveness of treating depression with psychedelics and saw these were related to changes in the amygdala.

Griffiths et al. (2016) used a random, double-blind cross-over trial to find if psilocybin helped treat depression and anxiety in cancer patients. They found that after moderate-large doses of psilocybin, the treatment group faced significant decreases in death anxiety and depression and increases in quality of life, meaning, and optimism compared to the placebo group. Community observers also observed these changes in the participants.

So, from what we can tell, psilocybin can treat major disorders and probably causes neurogenesis in the brain. 

Anyways, what does this mean in the long run?

Stoned Ape Hypothesis

The following hypothesis has been heavily mocked or ignored by the scientific community. And it’s understandable why. It sounds crazy. But I ask the reader to suspend their disbelief for just a moment and consider the possibility. One central mystery in modern evolutionary biology is the doubling in brain size for some two million to two hundred thousand years. Thus far, little plausible explanation has been given for why this occurred. In 1994, Terence McKenna proposed the Stoned Ape hypothesis to argue that the size of the brain increase was due to epigenetic neurogenesis, which happened through the casual consumption of Psilocybe cubensis. 

Why does McKenna’s view even make sense? As our primate ancestors left the jungles and traveled the desert areas, they needed to look for food. When you look for food, you’re typically looking for things like footprints and dung as they tell where animals have been.

The most prevalent fleshy mushroom found within animal dung, like that in hippopotami, cows, etc., is Psilocybe cubensis. We now know that 22 primate species consume mushrooms, giving this theory some more credence.

Hence psilocybin inclusion in the diet shifted the parameters of human behavior in favor of patterns of activity that promoted increased language; acquisition of language led to more vocabulary and an expanded memory capacity. The psilocybin-using individuals evolved epigenetic rules or cultural forms to survive and reproduce better than other individuals. Eventually, the more successful epigenetically based styles of behavior spread through the populations along with the genes that reinforce them. In this fashion, the people would evolve genetically and culturally.

The issue is proving psilocybin usage is beneficial or that it even increased intelligence in some way. That is where the theory of psychedelics and IQ comes in.

Do Psychedelics Increase Intelligence?

Even then, the amount of studies is minimal. That said, most indicate a potential increase, albeit a probably small one. Here is a table summarizing the research I found:

I should note that any increase at all is potentially beneficial. When discussing the brain size increase, we are talking 200,000 years to 2 million years. If our primate ancestors were consuming these drugs every day, perhaps multiple times a day even, then the effects of one dose being minor are radically multiplied insignificance. Since psychedelics may increase intelligence, there is undoubtedly a stronger argument for the Stoned Ape Hypothesis.

Modern Implications

If the Stoned Ape hypothesis is correct, then other things must be true about psilocybin usage. We would have to show somehow that high doses of psilocybin are associated with language-making abilities. This latter is expected to be true because psychedelics are associated with a more significant tactile response and a greater love for your surroundings, finding beauty in more things and getting a more extensive response when touching, seeing, or listening to various things.

Once again, I ask the reader to suspend their disbelief for a moment. Say one of our ancient ancestors is looking through the desert for food and comes across Psilocybe cubensis. If it is responsible for extinguishing the conditioned fear response, we know he could certainly hunt better. The same goes for visual and audio perception. Additionally, the group may take these and experience greater empathy which is shown across many studies. This is of particular interest in the creation of civilization. Bravery and altruism are great things to have in coordinating a group.

And so, if this is true, perhaps we ought to change the way we view these drugs. We see their benefits, and if we could somehow give more credence to the Stoned Ape hypothesis, we would understand that we are forever indebted to them for allowing Homo sapiens to arise and create modern civilization. Indeed, it would almost cause mass participation in psilocybin usage.

A study done by Hendricks et al. (2017) found that psilocybin usage decreased criminal behavior by ~20 percent. Imagine the consequences if everyone took these drugs. A 20 percent drop in crime would be extraordinary.

But, maybe for more conservative readers, this is extreme, this is ludicrous, etc. Fine. Say psychedelics have some effect on intelligence. What could you do to make this beneficial to you? I can hardly advocate we treat these breathtaking experiences, which can be very anxiolytic for many people, as an automatic IQ increases.

But, more and more evidence is increasing towards the benefits of microdosing. This is essentially taking a very small dose of psilocybin or LSD, maybe five days a week. It can also be combined with Lion’s Mane, a legal, medical mushroom that encourages neurogenesis, and with niacin which spreads the effects around the brain, allowing more excellent coverage of regeneration of neurons.

Microdosing is known to be used by coders and business people in Silicon Valley. And if it is all that helpful for things like creativity and cognitive functioning in general, then it will automatically put these people at an advantage. A small dose will not bring about any visuals, at least after the first day of microdosing, and so it will not have the same anxiolytic effect large amounts of psilocybin might have.

Psychedelics May Have an Effect on Intelligence

In conclusion, I think the Stoned Ape hypothesis is certainly plausible, especially with some, however non-conclusive, evidence that psychedelics may increase intelligence. If this is true, we may consider rethinking how we view our relation to psilocybin and mushrooms in general, perhaps.

We still can’t prove the Stoned Ape hypothesis, but we could demonstrate that psychedelics affect intelligence. It requires a proper study, maybe two, which looks at the effects of one or more large doses in the first one and the effects of microdosing in the second one.

One may bring up the Algernon argument when discussing the lasting effects of psilocybin microdosing on IQ, but this is not all that important if one decides to continue dosing, especially with next to zero risks. Indeed, in a study using Lion’s Mane to help cognitively disabled people, there were substantial, positive effects on IQ, but if the user stopped dosing, then it went away. Overall, this whole thing needs more research, and I think it should be done in respect of free inquiry and the desire for scientific improvement.


5 Amazing Benefits of Psilocybin Mushrooms

Psilocybin mushrooms or “Magic Mushrooms” have long had an infamous reputation among western society. This is mainly due to the Convention on Psychotropic Substances act passed in 1971 as a knee-jerk reaction to the increased drug use and counterculture of the ’60s. Psilocybin mushrooms were lumped in with opioids and amphetamines in the most highly controlled category. Thankfully, due to increased understanding and research in recent years, the tide of public opinion is turning. Psilocybin mushrooms are now inching their way towards widespread decriminalization.

Another stigma the Psilocybin mushroom has to contend with is the fear of the “bad trip.” This comes from anecdotal horror stories of experimenters trapped in nightmarish hallucinations or injuring themselves through panic. An experience such as this can be a consequence of misuse of psilocybin, particularly mixing with other drugs or alcohol.

In the right “set and setting,” psilocybin can be a truly fantastic tool for mind expansion, personal growth, and dealing with trauma.

‘SET’ – refers to the mindset a person brings to the experience. The mental state is critical as any thoughts, feelings, or preconceived notions may be amplified during the incident. A person should be relaxed, well-informed, and free from any other substances such as alcohol.

‘SETTING’ – refers to the physical and social environment in which the experience takes place. It should be somewhere safe and calm, with people you know and trust. Psychedelics often enhance emotions, so an uncontrollable hectic environment is likely to cause stress. It is also a good idea to turn off phones and get rid of any other distractions.

Here are five potentially life-changing benefits of a Psilocybin experience:

  1. Dissolution of ego
  2. Break negative thought patterns
  3. Able to deal with buried memories & trauma
  4. Increased compassion & empathy
  5. Increased connection with nature & the world

Dissolution of Ego

One fantastic effect of a Psilocybin trip is the unleashing of the mind to break away from the constraints of the ego. The ego can be thought of as the conscious decision-making aspect of our minds – the concept of ‘self’ built up by years of learned behavior.

The ego is inherently self-interested, which is a valuable quality for survival and self-propagation. The problem comes with being unable to step outside the ego’s perspective, which is often clouded by subconscious emotions and reactions. Psilocybin dissolves the ego, allowing us to see the issues and emotions covering our thought processes with extreme clarity. It also allows us to step outside of our perspective and see the bigger picture and the view of other people. If focused properly, it allows for a deep exploration of the subconscious.

Breaking Negative Thought Patterns

We all follow specific thought patterns or habits of thinking. These are like pathways engrained in our minds through learned responses to familiar stimuli. They’re formed much in the same way as a physical habit, by repetition, but can be much harder to break as they’re less visible.

Positive thought patterns can often be beneficial. The problem arises when we develop negative or faulty thought patterns, which lead us to a downward spiral. Such prolonged negative patterns can often lead to depression. There may have been an event or trauma to initiate negative thoughts, then the pattern of negative thinking becomes ingrained and very hard to break.

Psilocybin can be a fantastic tool for breaking negative thought patterns and allowing for a clean slate.

The best analogy I have heard describes our minds as a ski slope with deep paths ingrained by constant skiing.

Psilocybin is like a snowplow flattening the piste, allowing skiers to move around in whichever direction they please.

In recent years research groups such as Johns Hopkins and Kings College of London have begun trials to support their hypothesis that psilocybin may help treat treatment-resistant depression, addiction, and PTSD, after some promising research.

Even for the relatively healthy mind, the breaking and re-examining of thought patterns can be highly beneficial.

Dealing With Buried Memories & Trauma

Our minds have ways of protecting us from emotional trauma, often burying traumatic experiences deep down in our subconscious. This allows us to go about our daily life with normality but usually has negative consequences. Buried trauma can fester away in the depths of our minds like a rotten apple at the bottom of a barrel. Eventually, the effects will begin to show themselves in our behavior and emotions, sometimes manifesting in depression or addiction.

Much in the same way, psilocybin allows us to dissolve the ego and change our thought patterns. It will enable us to break through our mind’s defensive barriers and confront these negative memories. This can often be a painful and scary experience, as any confrontation is. The lasting effects of dealing with these issues head-on, however, can be life-changing.

Psilocybin and other psychedelic therapy have been described as having as much beneficial impact as five years of regular treatment. Between 70 and 100% of participants in some studies have described psilocybin-assisted therapy as among the most

Personally meaningful and spiritually significant experiences of their lives.

An excellent documentary that highlights this potential use for psilocybin and other psychedelics is ‘Dosed.’ It follows the journey of a long-time addict as she seeks to find the route of her problems and overcome her addiction.

Increased Compassion & Empathy

Those who take psilocybin often become aware of significantly increased compassion and the ability to empathize. This is linked to the ability to step outside our egos and see things through the eyes of others. The increased empathy can have on relationships with others and conflict resolution is invaluable. If a person can empathize well, they are likely to have more friends and healthier relationships.

Studies have shown psilocybin to increase empathy while leaving our moral decision-making ability unchanged considerably. This suggests it doesn’t cloud our judgment but shows us other perspectives, resulting in better reactions & decision making.

Lack of empathy is linked with various mental disorders, including narcissistic personality disorder, psychopathy, and borderline personality disorder. It is yet to be seen what effects psilocybin can have on treating disorders such as these. Studies such as this one have had success in showing increased empathy in participants and increased well-being seven days after a psilocybin experience. This hints at the potential for treatment for a wide range of conditions.

Increased Connectivity With Nature and The World

Another effect of breaking down of “the self” is a feeling of connectivity to nature and the rest of creation.

In our 21st Century lives, we’ve become so disconnected from nature it becomes easy to pretend we’re somehow separate from the world, the plants, and the animals. We rule over other animals and take the world’s resources for granted, treating them like our personal supermarket.

When barriers put up by the ego are broken, the individual becomes aware of the oh-so-obvious fact that we are the world, we are nature. We are nothing but intelligent apes with godlike technological power.

One trick of the collective human ego is to convince us we’re special, that nature exists only to please us. One hero’s journey with some suitably potent Psilocybin mushrooms is enough to lay bare the absurdity of this illusion. All that then remains is the glaring truth that we as a species have been abusing and destroying our only home and our brothers and sisters.

I am convinced if each of the world leaders were to commit to a triannual dose of psilocybin, we would see the tide turn on the climate crisis we find ourselves in. Priorities would surely be better aligned with our planet, its inhabitants, and the long-term wellbeing of our species. One can only dream.


Psychedelic Psychotherapies

A few years ago, I heard an interesting piece on the NPR program Radio Lab about a study in the 1960s on the effects of psilocybin, the active drug in magic mushrooms. The investigation later dubbed the “Marsh Chapel Experiment” or “The Good Friday Experiment” was conducted to see if psychedelics could induce religious experiences in religiously predisposed people. Timothy Leary was one of the study’s principal investigators, and it has thus gained some fame (and notoriety) in scientific circles.

The Study

The results fascinated me. Of the 20 male graduate students selected for the study who were studying to become clergymen, 10 of them received a dose of psilocybin, and 10 of them received the vitamin niacin.

While they found that psilocybin did indeed induce profound religious experiences in all 10 of the psilocybin group, the most shocking finding was revealed when they followed up with the subjects years later.

Of the ten who received that single dose of psilocybin on that day, all of them went on to become clergymen, while 9 out of 10 who took niacin ended up eventually choosing different careers.

This is a tiny sample size. There were some issues with the study design and execution, so I’m suspicious of over-generalized reports of these findings–but damn, it makes you wonder.

While the scientific merits of these kinds of studies can be and still are debated, this was the first time I’d ever even heard of a psychedelic drug outside of the context of a Grateful Dead concert or the U.S. government’s secret LSD studies on military personnel and prostitutes. The neuroscience nerd in me couldn’t resist seeing what other research was out there.

Philly Medicine

As it turns out, in the past decade or so, the U.S. government has begun to allow some small, highly controlled, particular trials to study the effects of psilocybin in a few different settings, the most prominent of which is psychotherapy.

One of the most prominent of these studies came out in 2011, examining the effects of psilocybin on anxiety and depression in patients with advanced cancer. Again, the results were striking, though furthermore, the small scale of the study precludes its generalizability.

The 12 subjects acted as their controls, receiving both the placebo and the psilocybin treatment at different time points. After receiving the single, moderate dose of psilocybin, the researchers observed long-term decreases in anxiety and depression, as far out as six months after treatment.

Other studies have found that psilocybin can enhance recollection of autobiographical memories, reduce OCD symptoms, and alleviate cluster headaches.

Furthermore, while psychedelics have been used in other countries to treat various addictions, western medicine seems to be opening up to the idea of using them to treat drug abuse and alcoholism as well. Thus, many clinicians, though certainly not all of them, are beginning to see psychedelics as promising therapeutic tools.

Furthermore, psilocybin has been shown to operate on the brain’s serotonin system, which has long been a target of many pharmaceutical interventions for mental illnesses. One of the most widely prescribed antidepressants/anti-anxiety medications, Prozac, increases serotonin’s availability in the brain.

If you press a neuroscientist hard enough, however, he or she will eventually admit that no one knows the exact mechanism by which manipulating the serotonergic system alters one’s general mood. However, some new findings may hold at least part of that answer and help better understand the underlying neurological deficits associated with mood disorders like depression and anxiety.

This might also explain the delayed effects of many mood disorder drugs that operate on serotonergic systems. Most of these drugs are relatively specific to one type of neuron receptor and exhibit limited bio uptake. People often don’t report any changes in mood for several weeks. Repeated use over this time may be necessary to induce sufficient changes in neural firing patterns that cause behavioral and emotional changes. Researchers have long postulated that this time lag results from longer-term genetic changes required for the drugs to work. Such genetic changes would be necessary to establish long-term, stable changes in neural firing patterns as well.

This is Your Brain on Shrooms

If you follow any pop-science news sites, you’ve probably seen something recently about a study on the effects of magic mushrooms on brain activity.

In summary, researchers at Imperial College London found that a low dose of psilocybin, the active drug in magic mushrooms, led to interesting neural firing patterns. Namely, many of the brain areas typically “in sync” during normal, non-drugged states are not synchronized under the influence of psilocybin. In contrast, other sites that are not typically synchronized under normal conditions sync up when someone trips on funky fungi.

Psilocybin May Alleviate Symptoms of Mood Disorders

It’s been hypothesized that many psychopathologies are associated with abnormal patterns of neuronal synchrony. If this is the case with depression and anxiety, it would seem feasible that attempts to alter this irregular pattern could benefit someone suffering from one of these mood disorders.

It’s somewhat of a guess on my part. Still, psilocybin might alleviate symptoms of mood disorders by scrambling the abnormal neural firing pattern and “forcing”–or at least influencing–a brain to establish a new design. This oversimplifies the issue somewhat, but I find the idea intriguing nonetheless.

For one, It fits with the serotonin story. Serotonin is a likely candidate to regulate patterns of neural synchrony since it is one of the most widespread and diffuse neurotransmitters in the brain. While it’s been implicated in many brain functions, both normal and abnormal, its specific parts are often difficult to pin down. A more generalized process of neural synchrony might account for its elusive role in many brain functions studied to date.

Given these findings that new patterns of neural synchrony emerge when someone is under the influence of psilocybin and that psilocybin has been shown in some cases to alleviate mood disorders, it seems feasible, then, that a critical function of serotonin in regulating mood is regulating the synchronous activity of networks of neurons.

This is overly simplistic, but many people advocate that people with mood disorders get out and try new things. Perhaps one way this works to get people out of a rut is by establishing new neural firing patterns or temporarily mixing them up.

This generally takes some time, and people gradually start to feel better (if they do at all). Psilocybin might instead be an exceptionally potent neural intervention in this sense, evidenced by its apparent long-term effects after only a single dose.


How Long Does Molly Stay in Your System?

After taking any drug, including molly, you may wonder how long the drug stays in your system.

There can be many ways to detect it from your system, and there are different time intervals for which it stays in your body.

Typically, molly is considered to be a mixture of many other drugs. It is impossible to know how long it will take for molly to wear off because of the various factors affecting its presence in the system.

Here are some of the ways that will make it easy for you to understand the procedures.

Is it Detectable in The Blood Test?

When you take pure MDMA, it cannot be detected by the standard test used for drug testing.

However, in some tests, when the test is explicitly performed to determine the presence, it can be detected. So, you should have the proper knowledge of how to get molly out of your system to stay tension-free.

How Can You Pass The Drug Test?

There are several things you can do to pass the drug test. Drinking detox drinks may be the best solution in these situations.

Drink the detox an hour before taking the test, and it will make your urine test molly free. With this solution, you do not have to worry about ecstasy being detectable in your urine because these drinks work effectively on all kinds of drugs.

All sorts of toxins are flushed out from your kidney and system, and there will be no traces left. There will be no chances of positive results because of the decrease in the drug metabolism.

Drug Tests to Detect Molly in Your System

Below, are some of the drug tests that are generally conducted to detect the presence of molly in your system. The time for which it stays in your system is also mentioned.

Detection Through Blood Test

One way molly may be detected is through a blood test. When you are looking for a solution to getting molly out of your system in 24 hours, a blood test is the best solution.

When you take a single dose of molly, it will not be detected in your blood after 12 hours of usage, while in the case of multiple quantities, it is possible to see the drug in your system after 24 hours.

Detection Through Urine

The most common type of drug test is through urine. In the case of molly, the detection in your urine can be done within one to three days of drug intake.

When you take a single dose, it will not be detected in your urine after three days. If you take multiple doses of the molly, the results will be positive after even 2 to 5 days of intake.

Saliva Test

When you take just a single dose, it will be detected from your saliva after 1 to 3 days of intake.

However, the intake of multiple dosages of MDMA will be detected even after five days of use.

Hair Test

The answer to the question of how long molly stays in your hair is three months.

No matter how much you take, either single or multiple, the time it takes for molly to be completely out of your system in a test will be the same.

This is the most extended time for which the traces of the drug remains in your body. However, the results may also vary according to the situation.

The Importance of Testing Your Molly

After knowing how long molly lasts in your system, you should also know that many drugs claiming to be pure MDMA are laced with harmful substances.

Many people have died or have ended up at the ER because of these harmful substances.

Knowing how long molly stays in your system is not enough. It would be best to take the necessary precautions to make sure you are not taking any molly that has been adulterated with other substances.

Furthermore, avoid alcohol usage after taking molly because severe dehydration will increase your body’s temperature. Patients with hypertension should strictly avoid the use of molly because it can prove fatal.

So Always test your molly and be safe!


Psilocybin Shows Promising Results For Patients With Cancer

Millennials were the only ones experimenting with magic mushrooms. In recent years, psilocybin has become very popular, and now scientists are looking at its effects on patients with cancer.

Psilocybin Could Benefit Patients With Cancer

Centered on two new analyses, magic mushrooms, or perhaps the psychedelic drug psilocybin, could significantly benefit patients with cancer tumors experiencing anxiety and major depression.

According to a new study led by researchers at New York University, a single dose of psilocybin found in psychedelic mushrooms has been found to significantly reduce anxiety and depression in patients with cancer for up to several months.

The findings show that a one-time treatment of psilocybin, whose use required federal waivers because it is a banned substance, brought instant relief to cancer patients.

The effects lasted for more than six months in 80 percent of the 29 study subjects monitored. This data was based on clinical evaluation scores for anxiety and depression.

All patients in the study, primarily women from the ages of 22 to 75, were patients at the Perlmutter Cancer Center of NYU Langone. They had either advanced breast, gastrointestinal, or blood cancers and were diagnosed with severe psychological distress.

All patients were counseled by psychiatrists, psychologists, nurses, or social workers and were monitored for side effects and improvements in their mental state.

Our results represent the strongest evidence to date of how beneficial psilocybin therapy has the potential to heal patients with cancer-related psychological distress.

Stated the lead investigator Stephen Ross, M.D., director of substance abuse services in the Department of Psychiatry at NYU Langone.

If larger clinical trials are also proven to be successful, then we could ultimately have a safe, effective, and inexpensive way to alleviate the distress that increases suicide rates among cancer patients.

Said Ross, also an associate professor of psychiatry at NYU School of Medicine.

Study co-investigator Jeffrey Guss, M.D., a clinical assistant professor of psychiatry at NYU Langone, states that magic mushrooms have been studied for decades and proven effective. He adds that none of the study participants experienced any serious adverse effects, such as hospitalization or other severe mental health disorders.

Although magic mushrooms’ neurological benefits are not entirely understood, psilocybin has been shown to activate parts of the brain also affected by the neurotransmitter serotonin, which regulates our anxiety and mood. Depression has also been linked to serotonin imbalances.

For the study, half of the subjects were randomly given 0.3-milligram doses of magic mushrooms, while the rest of the patients received a placebo (250 milligrams of niacin).

About halfway through the study’s monitoring period (after seven weeks), all participants switched treatments. Those who were initially given magic mushrooms took a single dose of the placebo, and those who first took the placebo then received magic mushrooms. Neither the patients nor researchers knew who had first received the psilocybin or the placebo.

The placebo control, randomization, and double-blind procedures maximized the validity of the results of the study, said Guss.

One significant finding was that reductions in levels of depression and anxiety lasted for the remainder of the study’s extended monitoring period, eight months, for those who took magic mushrooms first.

Co-investigator Anthony Bossis, Ph.D., a clinical assistant professor of psychiatry at NYU Langone, said that the patients who took magic mushrooms also reported improvements in their quality of life.

They went out more, had tremendous energy, got along better with family members, and did well at work. Several other patients also reported an increase in altruism, peacefulness, and spirituality.

Bossis stated that the study showed that psilocybin facilitated experiences that drove psychological distress reductions. He also mentioned that if it’s effective for cancer patients, then it may also be effective for everybody.

However, Bossis cautioned that patients should not consume psilocybin independently or without supervision by a physician and a trained counselor. He also said that magic mushroom therapy might not work for everyone, and people with schizophrenia and adolescents should not be treated with psilocybin.

The NYU Langone-led study, appearing in the Journal of Psychopharmacology, was published side by side with a similar study from Johns Hopkins. This study was also endorsed in 11 accompanying editorials from leading experts in psychiatry, addiction, and palliative care.

Based on experts, magic mushrooms ease stress, anxiety, and depression.

The common effects magic mushrooms had on many patients were a sense of love and being “one” with everything. It caused a change in the brain or neuroplasticity.

Studies using MRI imaging show psilocybin altering the brain to action, allowing for communication with regions in your brain that typically do not connect. The study shows a breakthrough for psychotherapy and researchers alike.

Profound Change on a Patients Life

In the Time Journal article, Dinah Bazer explains her experience going with a single dose of psilocybin in an analysis of NYU Langone hospital.

Dinah said that she felt scared and was initially “tumbling through space.” Right after being calmed by the researchers guiding her, she could relax and see her fear as a dark object inside her body. She took control and ordered the black muscle to go away, and it faded.

After that, she started to feel unusual. My spouse and I felt overwhelmed, at peace, and euphoric. The feeling of immense light lingered on for weeks, and after four years, I still feel the same effects at times.

My fear and anxiety had been removed, and it hasn’t been back. The experience changed how I viewed life. I used to imagine what the idea will be like if the tumor came back, although I no longer think about it the same way as I did years ago. When My spouse and I don’t feel well, thought processes of a recurrence creep in my mind; however, I no longer have anxiety.

The Benefits of Magic Mushrooms are Promising

The benefits of magic mushrooms look promising. Many individuals have experimented with psilocybin, and now, most of us trust this mind-altering drug that affects our emotions in a way that:

  • Benefits our emotional health
  • Heightens spiritual expansion
  • It brings peace and happiness

Like with any drug, it’s essential to think about the physical complications involving the use of mind-altering medications, which can cause vitamin/mineral deficiencies, failing liver complications, cognitive troubles, and much more. However, the benefits outweigh the consequences.


The Challenges of Psychedelics in Psychotherapy

The study and use of psychedelics in psychiatric therapy have been exceptionally repressed by current paradigms in psychiatry and psychology, the biological symptom-suppression transformation in psychiatry, the prohibitionist drug war, and modifications in the insurance industry that limit patients’ access to care.

Concepts and Paradigms

The power of concepts or paradigms to arrange and limit thinking in researchers and specialists is displayed in the current obsession for quick one-step biological options to practically every kind of psychological distress or disorder.

The symptom-reducing or eliminating anti-anxiety, antidepressant, and antipsychotic medications have shifted the focus of psychiatric training from dynamic psychiatric therapy and psychoanalysis to psychopharmacology.

Massive funding offered for research study in this area is a collusion between the government and the pharmaceutical industry.

As valuable as symptom-relieving drugs may be, when used properly, they are not sufficient to address the complexities of addiction and conflicted human personality.

Psychedelics are a totally new family of medicines that can amplify the healing properties of a psychotherapy relationship and transport patients into life-altering realms of consciousness.

Although these medicines are no more panaceas than symptom suppressors, they are worthy of exploration and advancement.

Psychedelics need to be studied in methods appropriate to comprehending the nature of their action.

Consciousness expanding drugs are distinctively sensitive to the attitudes and beliefs of the doctors using them and to the setting in which they are provided.

The War on Drugs

There is a 17 billion dollar dark cloud on the horizon of freedom in the United States. The federal budget for the “war on drugs” has actually grown 3,200% since 1970.

More than 400,000 citizens are in prison on controlled substance convictions (Shenk, 1999).

The prohibitionist drug war brought us an attitude toward drugs of abuse that is oddly reflected in etymology. The Greeks had a word for it: phármakon indicated drug, pharmakós, nevertheless, meant scapegoat!

Our public law towards drugs of abuse reflects these original paronomastic confusions. With the exceptions of alcohol and tobacco, our laws scapegoat drugs for the social ills that foster their abuse (Escohotado, 1999).

Substance abuse and dependency are sequels to misery. Such despair is frequently, though not always, rooted in the despondence of social injustices.

The federal government lavishes billions locking up drug dealers, interfering with the internal politics of drug-producing nations, and intercepting deliveries of controlled substances.

This policy casts a totalitarian shadow both at home and abroad. At the same time, the obstacle to provide education and chance rather than penalty for the disadvantaged is avoided.

In 1962 and 1965 ever more oppressive limitations were put on genuine clinical research with LSD and other hallucinogens.

In a May 1966 congressional hearing Senator Robert Kennedy asked how drugs that were worthwhile six months before all of a sudden ended up being awful.

The frightening answer to his question was that LSD had left the lab and recorded the bodies, minds, and hearts of America’s defiant youth (Mangini, 1998; Shenk, 1999).

After hearing the evidence Kennedy gave a courageous admonition:

Maybe to some extent, we have forgotten the reality that (LSD) can be extremely valuable in our society if utilized effectively (Subcommittee on Executive Reorganization, 1966 p. 63).

In 1968 the American Journal of Psychiatry brought a short article about the devastating effect of negative promotion and federal constraints on legitimate LSD research (Dahlberg, 1968).

The paper records a disgraceful psychiatric witch hunt. Ongoing research study projects were canceled and authentic researchers were attacked as “kooks”.

Previously approved projects were denied supplies of LSD by the National Institute of Mental Health (Pollard, 1966).

By 1970 LSD became illegal. It was lumped with heroin and placed by the Drug Enforcement Administration into the new Schedule I category: drugs that have no acknowledged medical use and have high abuse capacity.

This act neglected and denied numerous articles documenting the value of psychedelics as adjuncts to psychiatric therapy.

Monetary Restrictions

In the United States, the insurance coverage market has evolved into “health maintenance organizations” (HMOs) and “Managed Care” plans.

These brand-new entities manage clients’ access to healthcare and define eligibility for reimbursement according to a brand-new series of often-secret guidelines.

It is clear to the majority at this moment that this system serves to limit patients’ access to care. Managed care has actually efficiently cut the delivery of both inpatient and outpatient care in the private sector.

A national research study of independently guaranteed individuals looked at 3.9 million psychological health care claims from 1993 to 1995.

The scientists concluded:

For patients utilizing outpatient services just, those detected with substance abuse experience the largest decrease in expenses (23.5%) (Leslie & Rosenheck, 1999).

The August 1999 Consumer Reports published a study of 19,000 people guaranteed by HMOs. People with serious health problems had more problems getting care than did people without serious health problems.

Both groups had problems getting care. Problems took place from just 5% of the time to as much as 30% of the time (Kagan, 1999).

Many people discover that, when you require it, the existing healthcare delivery system does not deliver. Salaries of HMO executives soar above the norm for other chief executives in the country.

Intervention in the definition of illness and delivery of care has had an extensive effect on psychiatric therapy and addiction treatment reimbursement.

The tendency is to define treatment as what is reimbursed by the ruthlessly budget-minded insurance industry.

By comparison, the Veteran’s Administration reports reduce in inpatient care paralleled by a boost in outpatient service delivery. The general public sector is liable to its constituents whereas the private sector views information as proprietary and private.

This post highlights the shortsighted nature of this approach to treatment. It highlights changes in federal government financing for inpatient addiction treatment and research study likewise moves toward symptom-oriented approaches that are superficial and hardly ever sufficient.

An Age of a New Era

We need to psychedelics in another light. Studies have shown that psychedelics have shown promising results in treating psychological disorders and having lasting effects than conventional medicine.

We need more funding in learning and researching psychedelics to further understand the drug’s amazing healing powers. Only then can we progress and help heal people that are in desperate need of a cure.


Psychedelics Can Unlock The Mysteries of The Brain

Research into the inmost mysteries of the brain consisting of consciousness and mental illness had been cut by the restriction of psychedelic drugs.

Researchers must have access to unlawful hallucinogens such as LSD and psilocybin to help them progress in brain research.

Treatment For Anxiety and Schizophrenia

The federal government’s former drug advisor Professor David Nutt who is now a professor of neuropsychopharmacology at Imperial College London, claims that hallucinogens such as magic mushrooms may provide insights into anxiety and schizophrenia.

Professor Nutt said that researchers may discover treatments for conditions such as schizophrenia by utilizing modern-day techniques to study the impacts of psychedelic drugs on the brain.

Neuroscience must be trying to comprehend how the brain works, said Nutt.

Psychedelics alter the brain in, perhaps, the most profound way of any drug, a minimum of in terms of comprehending awareness and connectivity. Therefore we must be doing a lot more of this research.

More Research Needs to be Done

Nutt also states that it’s remarkable that 40 years of advances in brain imaging innovation and there’s never been a study about this prior to.

It’s a scandal, it’s outrageous the fact that these research studies have not been done. And they have not been done simply because the drugs were unlawful.

Speaking with the Guardian ahead of a lecture he will give at a University College London neuroscience seminar on Friday, Nutt stated that a volunteer for a current experiment pulled out of the research study since he was worried that being in a study with a so-called illegal drug might imply he couldn’t travel to some countries, such as America. To hinder research to that degree is an outrage.

Nutt’s views will challenge federal governments all over the world which, largely, classify hallucinogens as damaging and illegal.

The professor is used work alongside the authorities. In 2009, the UK’s health secretary, Alan Johnson, took him off from his post as chair of the government’s Advisory Council on the Abuse of Drugs for openly specifying that alcohol and tobacco were more hazardous than LSD, ecstasy, and cannabis.

Successful Treatments Using LSD

Numerous clinical trials of psychedelic drugs such as LSD were performed in the 1950s and 1960s, and successful treatments, consisting of one for alcohol addiction, came out of the work.

Because LSD was prohibited all over the world, nevertheless, the variety of clinical research studies has actually dropped to essentially absolutely nothing, and there have been no studies using contemporary imaging techniques such as magnetic resonance imaging (MRI) to take a look at what parts of the brain are affected by it.

Promising Treatment For Schizophrenia

Nutt recently released research, with associates at Cardiff University, on the results of psilocybin– the active component in magic mushrooms– on the brain.

His team had actually presumed the drug may increase activity in specific parts of the brain, to describe the experience that users get when they consume magic mushrooms.

Rather, MRI scans of 30 healthy volunteers showed that psilocybin seemed to reduce activity in the regions of the brain which link up different areas. The research study was published in January in the journal Proceedings of the National Academy of Sciences.

This is an extremely essential method of alarming the brain to comprehend the nature of consciousness, stated Nutt.

At his lecture on Friday, he will examine whether psilocybin’s results on the brain can be used as a model for psychosis.

Some of the brain alterations viewed as a result of taking psilocybin, he said, are similar to those seen in the brains of people with prodromal schizophrenia.

Psilocybin seems to reduce the actions of a brain system called the “default mode network” which is active whenever an individual is, for instance, reflecting on the world rather than participating in a specific activity.

The “task-positive network” is engaged when an individual focuses on a specific job and it operates out of phase with the default mode network.

However in schizophrenia, the networks are far more in phase and, under psilocybin, they are totally in phase.

So, we’re thinking [psilocybin] might be an intriguing design for early stages for schizophrenia, it may allow us to evaluate brand-new drugs, said Nutt.

When individuals start to become psychotic, their ego limits break down, the relationship between them and the world gets disrupted and the relationship between their various inner experiences gets mixed up. Eventually, they begin hearing their own thoughts as someone else’s voice.

That breakdown of connectivity in the brain is very common in schizophrenia.

Nutt states that if they can produce this in a laboratory in a normal volunteer, they can then search for new treatments and it is far more effective to do than search for young people who are beginning to develop their health problem and it’s morally more acceptable too.

Psychiatric Therapy Using MDMA

Nutt and his associates are also studying prospective uses for ecstasy, likewise referred to as MDMA.

The restorative worth of MDMA for psychiatric therapy has actually been commonly understood till it was banned and has hardly been studied given that.

There have actually only been a couple of MDMA imaging research studies, but none of them utilizing innovative innovations, so we’re doing that at present.

In cooperation with Robin Carhart-Harris at Imperial College London, Nutt likewise wants to enhance his research study into more hallucinogens such as LSD and ibogaine, a derivative of African root bark, which is utilized to deal with dependency in Thailand and Cambodia.

Laws Make Researching These Drugs Difficult

Performing such work is typically tough for scientists, however, since they need to make such lengthy applications for licenses to utilize illegal drugs.

And even if the research went ahead and revealed benefits from the drugs, it is unlikely physicians would be enabled to recommend them.

Nutt recently required the UK’s classification system of drugs to be rewritten to reflect more accurately their relative harms and required a regulated technique to making drugs such as MDMA and marijuana offered for medical and research functions.

Laws, which are arbitrary, actually make it practically impossible to research these drugs, stated Nutt last month. The impact these laws have actually had on research study is greater than the effects that George Bush stopping stem cell research has had, since it’s been going on since the 1960s.